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3 Heart rate changes due to changes in pacemaker potential

Rising slope (dV/dt) of prepotential e. g.

Sympathetic stimulation, epinephrine. K+ outside \ fever

diastolic

200 400 ms

2 Duration of myocardial action potential depends on the rate of excitation

(after Trautwein et al.)

4 Factors influencing conduction of the action potentials (AV node)

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