Endothelial dysfunction and diabetes mellitus

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Although the link between diabetes and cardiovascular disease is not well understood, endothelial dysfunction may be implicated in the pathogenesis of diabetic vascular disease. The evidence of endothelial dysfunction in diabetes comes largely from studies measuring the endothelial substances that mediate fibrinolysis and coagulation. Chapters 2 and 6 give detailed descriptions of these studies. For example, plasminogen activator inhibitor-1 levels are increased, whereas fibrinolytic activity and prostacyclin levels are decreased in both type 1 and 2 diabetes (42-45).

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Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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