In the cytoplasm (perikaryon) of nerve cells and in the dendrites, basic dyes bring out fine or coarse granules, which are called Nissl bodies (chromophilic or Nissl substance) after their discoverer (cf. Fig. 20). Nissl bodies are portions of the rough endoplasmic reticulum (rER) (cf. Fig. 24). The base of the axon, the axon hillock, is free of Nissl bodies and so is the axoplasm. The left process from this multipolar nerve cell from the columna anterior of the spinal cord is in all likelihood an axon (neurite). The other processes are dendrites. Note the large cell nucleus with its clearly outlined nucleolus. The nerve cell is surrounded by a neuropil. Neuropils are the structures that fill the spaces between perikarya. The neurophil elements consist of glial cells with their processes, the processes of nerve cells and capillaries.
1 Glial cells
Stain: Nissl cresyl violet; magnification: x 400
Was this article helpful?
This guide will help millions of people understand this condition so that they can take control of their lives and make informed decisions. The ebook covers information on a vast number of different types of neuropathy. In addition, it will be a useful resource for their families, caregivers, and health care providers.