Prostate Gland

This figure shows the epithelium of the prostate gland at higher magnification. The lining of the branched tubuloalveolar glands consists in part of ¡2 single-layered, in part of two-layered or multilayered epithelium. The shapes o of the epithelial cells range from flat to cuboidal to columnar. Dependent on the secretory activity and the presence of hormones, epithelial cells appear in different configurations. Age also influences the appearance of the epithe-§ lium. The apical regions of the gland cells contain secretory granules, which bind variable amounts of stain. The apical regions also contain lipid granules, ^ glycogen granules and vacuoles. Occasionally, cytoplasmic protrusions are pinched off from the secretory cell and sequestered into the lumen. Undif-g ferentiated, flattened basal cells are found between the secretory epithelium and the basal membrane. They are considered progenitor cells of the gland cells. The connective tissue fibers are stained red and the muscle tissue appears yellow (cf. Figs. 539, 541).

Stain: van Gieson iron hematoxylin-picrofuchsin; magnification: x 400

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