Capillaries with fenestrated endothelium (see Fig. 299) must be distinguished from fenestrated, discontinuous sinusoidal capillaries. Their endothelial layer shows gaps [2. The figure shows a section of a liver capillary ( sinusoids of the liver lobule). The endothelium displays 0.1 to 1.0 |im-widegaps Exchanges between capillary lumen and the Disse space [3 (spatium perisinu-soideum) proceed via this discontinuous endothelium. There is no basal membrane. The surfaces of the liver cells (hepatocytes) next to the Disse space are covered with microvilli of different sizes. There are reticular and collagen fibers present in the Disse space (cf. Fig.449). With a diameter of 30-50|im, discontinuous sinusoidal capillaries are wider than other types of capillaries.
1 Capillary lumen 3 Disse's space
2 Endothelium 4 Liver cell cytoplasm Electron microscopy; magnification: x 8500
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