Inhaled corticosteroids

1. Regular use of an inhaled corticosteroid can suppress inflammation, decrease bronchial hyperresponsiveness and decrease symptoms. Inhaled corticosteroids are recommended for treatment of patients with mild or moderate persistent asthma as well as those with severe disease.

2. Adverse effects. Inhaled corticosteroids are usually free of toxicity. Dose-dependent slowing of linear growth may occur within 6-12 weeks in some children. Decreased bone density, glaucoma and cataract formation have been reported. Churg-Strauss vasculitis has been reported rarely. Dysphonia and oral candidiasis can occur. The use of a spacer device and rinsing the mouth after inhalation decreases the incidence of candidiasis.

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