Use: Most organic and inorganic materials, ASA, acetaminophen, barbiturates, glu-tethamide, phenytoin, theophylline, TCAs. Dose: Early (within 1-4 hours) administration of a flavored 8:1 water slurry, 10:1 AC drug, 1-2 g/kg body weight (bw). Side effects: Vomiting, aspiration, diarrhea, later constipation, possibly small bowel obstruction (SBO); AC is usually combined with a cathartic, particularly 70% sorbitol preferred over Mg citrate.
Decontamination: Multi-Dose AC (MDAC)
Chemistry: Saline and glucose-based cathartics composed of nonabsorbable cations (Mg, Na) that establish an osmotic gradient to draw water into gut.
Mechanism: Magnesium citrate and sorbitol are osmotic cathartics.
Contraindications: Adynamic ileus — SBO, abdominal trauma, diarrhea, renal failure (Mg citrate), more than initial dose of MDAC. Oil-based cathartics (mineral oil) are hydrocarbons (HCs), increase aspiration risk, and increase HC and mothball absorption.
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Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. Sometimes you just want everyone to leave you alone and sleep to escape the pain. It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life.