1

OxyHb + SO

2H2O

figure 22.3 The shared toxicities and similarities in treatment strategies for cyanide or hydrogen cyanide gas poisonings. The shared impact of cyanide (CN) or hydrogen sulfide (H2S) gas poisoning on the cytochrome oxidase electron transport system and the oxygenation of hemoglobin. This diagram also depicts the rationale for inducing methemoglobinemia with nitrites in the detoxification of both CN and H2S poisoned patients.

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