Sympathomimetic Toxidrome

Features: "Fight or flight" = hypertension, tachycardia, sweating, fever, excitation-psychomotor agitation, tremor, seizures, dilated pupils. Causes: Amphetamines/diet drugs, cocaine, theophylline, caffeine, methylphenidate, mono-amine oxidase inhibitors; over-the-counter cold medications, especially those containing phenylpropanolamine (PPA), ephedrine, and pseudoephedrine.

Mechanisms: Increased release of catechol-amines (amphetamines), blockade of cat-echolamine re-uptake (cocaine), inhibition of catecholamine metabolism (monoamine oxidase inhibitors), indirect adrenergic receptor stimulation (ephedrine). Antidote: Beta-blockers.

An Addict's Guide To Freedom

An Addict's Guide To Freedom

Get All The Support And Guidance You Need To Be A Success At Understanding And Getting Rid Of Addictions. This Book Is One Of The Most Valuable Resources In The World When It Comes To New Ways To Understand Addicts And Get Rid Of Addictions.

Get My Free Ebook


Post a comment