Development of the Human Immune System

Ramona Leibnitz CONTENTS

Introduction 22

Development of the Fetal Immune System 22

Hematopoiesis 23

Microenvironments 24

Interuterine Environment 25

Major Components of the Fetal Immune System 25

T Cells 25

Natural Killer Cells 27

B Cells 27

Macrophages and Dendritic Cells 28

Complement 29

Development of the Newborn Immune System 29

Major Components of the Newborn Immune System 31

T Cells 31

Natural Killer Cells 32

B Cells 32

Macrophages and Dendritic Cells 33

Complement 34

The Adult Immune System 34

Manipulators of the Developing Immune System 34

Summary 35

References 35

0-415-28457-0/05/$0.00+$1.50 © 2005 by CRC Press LLC

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