Overview

^ Located in right, upper quadrant of abdominal cavity under the diaphragm

^ Both an exocrine and an endocrine gland

• Exocrine secretion (bile) is stored in the gall bladder and released into the duodenum. This secretory product contains bile acids that aid in the emulsification of lipids, bilirubin (the breakdown product of hemoglobin), phospholipids, and cholesterol.

• Endocrine function is the synthesis of plasma proteins, including albumin, clotting factors, and lipoproteins that are released into the liver sinusoids.

^ Additional functions include the metabolization of digested food, storage of glucose as glycogen, and detoxification.

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