Three types of alopecia can be detected in patients with LE (Sontheimer and Provost 1996). In addition to the permanent scarring alopecia associated with discoid lupus lesions, patients with SLE may experience transient alopecia with increased disease activity. Two types of transient hair loss, a result of the severe catabolic effect of the

Table 7.4. Comparative histologic findings in chilblain lupus erythematosus (LE) vs idiopathic chilblains (see Cribier et al. 2001,Viguier et al. 2001)

Histopathologic Findings

Patients (%)

Chilblain LE (n=


Idiopathic Chilblains (n=17)

Epidermal spongiosis



Basal vacuolation



Perieccrine infiltrate



Dermal edema



lupus disease flare, have been detected. One is classic telogen effluvium, in which the patient develops prominent and at times alarming loss of hair all over the scalp. If the patient's SLE is a chronic active disease process, the telogen effluvium may persist for a prolonged time. However, with quiescence of the lupus disease process, normal growth of hair resumes. The second form of alopecia, related to a flare of the SLE process, is termed "lupus hair" or "woolly hair". It is most likely a type of telogen effluvium characterized by the development of thin, weakened hairs most prominent at the periphery. These hairs easily fragment; the hair becomes unruly, giving a characteristic appearance. Conceptually, it is theorized that with the negative nitrogen balance of the lupus disease flare, normal hair growth is interrupted, leading to a reduced number of thin, weakened hairs, which easily fragment above the surface of the scalp.

Alopecia areata has also been seen in patients with SLE. In all probability, it probably reflects the occurrence of two autoimmune disease processes in the same individual.

Hair Loss Prevention

Hair Loss Prevention

The best start to preventing hair loss is understanding the basics of hair what it is, how it grows, what system malfunctions can cause it to stop growing. And this ebook will cover the bases for you. Note that the contents here are not presented from a medical practitioner, and that any and all dietary and medical planning should be made under the guidance of your own medical and health practitioners. This content only presents overviews of hair loss prevention research for educational purposes and does not replace medical advice from a professional physician.

Get My Free Ebook

Post a comment