In summary, patients with LE may manifest a variety of skin lesions. A thorough evaluation of any given patient is needed before therapy. Patients may have factors that exacerbate their disease, such as light from the sun or from artificial sources, drugs, or smoking. If possible, therapy should begin with the removal of any identified exacerbating factors and include sunscreens, protective clothing, behavioral alteration, and topical corticosteroids. Calcipotriene or retinoids may be effective in some patients. Intralesional injection of corticosteroids and oral antimalarials are the other parts of a standard therapy program. The choice of alternative therapy is personal, and discussions of the risks and benefits should be carefully documented. Successful therapy for CLE is possible in almost all well-motivated, cooperative patients.

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