MicheLe L. Rosenbaum, Victoria P. Werth
Cutaneous lupus erythematosus (CLE) defines a spectrum of diseases, including subacute CLE (SCLE), LE tumidus (LET), discoid LE (DLE), and systemic LE (SLE). Of these, the most photosensitive are SCLE and LET. The anti-Ro/SSA antibody and the human leukocyte antigen (HLA) DR3 genotype are strongly correlated with SCLE but are rarely present in DLE (Lee and Farris 1999) or LET (Alexiades-Armenakas et al. 2003).
Photosensitivity defines a predisposition to developing lesions from the sun, as these patients have a normal range of minimal erythema dose compared with the general population (Sanders et al. 2003). Photoprovocation studies clearly demonstrate that ultraviolet (UV) light (UVA, UVB) (Kuhn et al. 2001a, b, Lehmann et al. 1990, Walchner et al. 1997), and visible light (Sanders et al. 2003) can provoke lesions in all photosensitive forms of LE (Cheong et al. 1994).
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Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.