NLE is a rare disease presenting in the neonatal period that resolves in the first 6 months of life. Associated disorders include transient thrombocytopenia, leukopenia, and a congenital heart block. Affected are children of mothers suffering from SLE. Clinically, children exhibit lesions as seen in SCLE. The causative agents are maternal IgG antinuclear antibodies (usually anti-Ro/SSA, less frequently anti-La/SSB, a-fodrin, and U1-RNP).
Histologic changes are similar to those of SCLE. However, infiltration at the dermoepidermal interface and vacuolar degeneration of the basal layer are more pronounced, sometimes with formation of clefts and edema of the dermis.
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Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.