Other Drugs

The list of drugs that have been associated with induction of lupus is very long. Some drugs, such as methyldopa, were not mentioned in the interest of brevity. There is also a new antiangiogenesis agent, COL-3, with a structure similar to tetracyclines, that has been reported to cause a lupus-like syndrome (Ghate et al. 2001). Estrogens have been reported to be associated with lupus, but that association is more likely due to the potentiation of idiopathic lupus. In the case of most other drugs associated with lupus, the evidence is too weak to have confidence that the association is causal.

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