Although there have been case reports of a lupus-like syndrome associated with other P-blockers, the only two associated with a significant incidence are practolol and ace-butolol. Practolol was one of the first P-blockers, and it was associated with a lupuslike syndrome and an unusual occulo-mucocutaneous syndrome that led to its withdrawal (Raftery and Denman 1973). This led some people to suspect that it might be a class effect, and this increased suspicion about other drugs in this class. In one study, ANAs were found in eight of nine patients treated with acebutolol, and there are also case reports of acebutolol-induced lupus (Booth et al. 1982).As mentioned in the "Involvement of Reactive Metabolites" subsection, practolol and acebutolol are the only P-blockers that are readily metabolized to aromatic amines.

Hair Loss Prevention

Hair Loss Prevention

The best start to preventing hair loss is understanding the basics of hair what it is, how it grows, what system malfunctions can cause it to stop growing. And this ebook will cover the bases for you. Note that the contents here are not presented from a medical practitioner, and that any and all dietary and medical planning should be made under the guidance of your own medical and health practitioners. This content only presents overviews of hair loss prevention research for educational purposes and does not replace medical advice from a professional physician.

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