Prognosis of Rare Variants of Cutaneous Lupus Erythematosus

A few studies have been reported concerning the disease courses in rare CLE variants. LE profundus/panniculitis is regarded to have a more benign prognosis than SLE. In 10 years of follow-up, only 4 (25%) of 16 patients were classified as having SLE according to ARA criteria (Watanabe and Tsuchida 1996). In other case series, only 4 of 40 patients fulfilled the criteria for SLE. The major morbidity in this series resulted from disfigurement and occasional disability related to pain; 7 (18%) of 40 patients had applied for disability. Death related to active panniculitis did not occur. The disease course was chronic, with symptoms reported for an average of 6 years, and characterized by periods of remission and exacerbation (Martens et al. 1999).

LE tumidus (LET) is a subtype of CLE with some peculiarities. Clinically, LET is characterized by erythematous, succulent, urticaria-like, nonscarring plaques with a smooth surface in sun-exposed areas. Reproduction of skin lesions after UVA or UVB irradiation is possible in 70% of the cases. The sex ratio shows an equal distribution between males and females. Nonspecific LE skin lesions are uncommon, and, usually, none of the patients can be classified as SLE, reflecting that LET is a CLE variant with a more benign course (Kuhn et al. 2000) (Table 14.3).

How To Deal With Rosacea and Eczema

How To Deal With Rosacea and Eczema

Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.

Get My Free Ebook

Post a comment