Variants of Lupus Erythematosus Lupus Erythematosus Tumidus

LE tumidus (LET) usually affects sun-exposed areas such as the face, back, and V area of the neck. Clinically, there are erythematous, succulent, edematous, nonscarring plaques (Kuhn et al. 2000). Histologically, LET is characterized by patchy lymphocytic infiltrates in the dermis. Mucin deposits are observed between the collagen fibers. The epidermis and the subcutaneous tissue are usually not involved (Kuhn et al. 2003).

Direct immunofluorescence depends on the duration of the lesion. In long-lasting lesions, usually there is deposition of IgG and IgM along the basement membrane (Kind et al. 1992). The differential diagnosis includes polymorphous light eruption, Jessner's lymphocytic infiltration of the skin, and pseudolymphoma (reactive lymphocytic infiltrate). Furthermore, reticular erythematous mucinosis (Steigleder et al. 1974) is regarded by Ackerman as a variant of LE.

Hair Loss Prevention

Hair Loss Prevention

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