Positron Emission Tomography

Whole body positron emission tomography (PET) with 18-F-fluorodeoxyglucose (18-FDG) allows malignant adrenal lesions to be recognized. The contribution of 18-FDG PET has been well evaluated in large studies in relation to lung cancer, and is highly accurate in differentiating benign non-inflammatory lesions from malignant disease. Using 18-FDG PET, these studies have shown a 100% sensitivity and specificity for the diagnosis of malignant adrenal mass when CT or MRI identify enlarged adrenal glands or a focal mass. Recent studies have reported false positive results as a result of 18-FDG uptake by pheochromocytomas and benign adenomas. For the diagnosis of a malignant adrenal tumour, the positive predictive value of 18-FDG PET was 100% and the negative predictive value (NPV) to rule out malignancy was also 100%. Within these study populations, 18-FDG PET also has the ability to detect metastatic lesions in non-enlarged adrenal glands, but its accuracy in this situation has not been fully evaluated. In addition, 18-FDG PET has the advantage of simultaneously detecting metastases at other sites. However, in some countries, PET is not readily available. Nevertheless, it is a useful tool for evaluating masses that are indeterminate by both CT and MRI. PET can substitute for percutaneous biopsy and has the advantage of being non-invasive and therefore a safer investigation for the patient [25].

Managing Diverticular Disease

Managing Diverticular Disease

Stop The Pain. Manage Your Diverticular Disease And Live A Pain Free Life. No Pain, No Fear, Full Control Normal Life Again. Diverticular Disease can stop you from doing all the things you love. Seeing friends, playing with the kids... even trying to watch your favorite television shows.

Get My Free Ebook

Post a comment