Padma 28, also known as Badmaev 28 and Gabyr-Nirynga, is a complex mixture of herbs sometimes recommended for MS. This herbal combination was developed in the late nineteenth century in the Buryat region of the Russian Empire by two physicians, Sul-Tim-Badma and Zham-Saram-Badma, also known as Dr. Alexander Badmaev and Dr. Peter Badmaev. The practices of these physicians were influenced by traditions of Ayurvedic and Tibetan medicine. Padma 28 is taken by mouth and contains more than 20 different herbs and calcium. It appears to have antioxidant effects and may mildly decrease immune system activity.
Padma 28 has been claimed to be effective for MS and other conditions, including heart disease, peripheral vascular disease, and asthma. In mice with EAE, an animal form of MS, consuming water that contains Padma 28 is associated with longer survival times and decreased death rates. A 1992 study in Poland evaluated Padma 28 treatment in 100 people with a progressive form of MS (2). Over the course of a year, one group of people received Padma 28 and the other group received no herbal treatment. In the treated group, 44 percent had some type of clinical improvement; none of the untreated people improved. This study is promising, but because specific details of its design are not available, the strength of the effect is not entirely clear.
The 1992 Polish study of 100 people reported no side effects. No other detailed toxicity information about Padma 28 is available.
Limited studies with Padma 28 suggest that it may be beneficial for MS. However, these studies are by no means conclusive, and limited information is available on the safety of this herbal preparation, especially for long-term use.
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