Cns

inflammatory response

Menin-gococci

Activated astrocyte

Endothelial cell

Macrophage

Activated astrocyte

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Hematogenous invasion of CNS

Adhesion molecule (adhesion of hematogenous cells)

Hematogenous spread of endocarditis

Bacterial endocarditis

Bloodstream

Diapedesis of leukocytes (migration from bloodstream)

Bacterial invasion

General inflammatory response

Blood-brain barrier lesion ( =o increased rmeability)

Hematogenous invasion of CNS

Granulocyte

Adhesion molecule (adhesion of hematogenous cells)

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