Causes

Neoplasms, infiltrative lesions, malformations, and neurosurgical procedures in the area of the pituitary gland are the most common causes of DI. Other causes of DI include trauma to the pituitary gland, vascular changes such as stroke and aneurysm, infection, pregnancy, and unknown reasons. The brain swelling that accompanies anoxic brain death may also lead to DI. In addition, certain drugs (lithium, demeclocycline, methoxyflurane, or amphotericin) or metabolic conditions can induce DI. Approximately 50% of the patients who develop DI have a familial or idiopathic (from unknown causes) form. In addition, congenital DI in neonates occurs as a result of malformation of the CNS.

0 0

Post a comment