Factors that contribute to the development of peptic ulcers include a genetic predisposition to ulcer formation; poor cell restitution; excessive acid secretion; stress; excessive alcohol intake; smoking; ingestion of aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs); and chronic use of drugs such as steroidal, potassium, or iodine compounds. The Helicobacter pylori bacterium, the principal causative agent of type B chronic gastritis, is also thought to be a major cause of peptic ulcers. Associated diseases include hyperparathyroidism, chronic lung disease, and alcoholic cirrhosis.

0 0

Post a comment