Diagnostic Highlights

General Comments: There are no specific serum laboratory tests or diagnostic procedures that conclusively identify IE, although some are highly suggestive of its presence. Special cultures or serologic tests may detect nonbacterial IE.

Abnormality with

Test Normal Result Condition Explanation

Blood cultures and Negative Positive for If patients have been on antibiotics, they sensitivities (three to microorganisms in are less likely to have positive cultures;

five sets of cultures 90% of patients three sets of blood culture should be over 24 hr) taken from separate sites over at least a

1-hr period before antibiotics are begun.

Other Tests: Complete blood count, M-mode and two-dimensional echocardiography, and transesophageal echocardiogram (TEE), transthoracic echocardiogram (TTE), two-dimensional cardiac ultrasound Doppler, electrocardiogram, rheumatoid factor

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