Gender Ethnicracial And Life Span Considerations

Males who inherit the genetic trait have hemophilia. Most females with the defective gene do not develop clinical manifestations because they usually inherit a normal X chromosome from the other parent. Hemophiliac males do not transmit the disease to their sons because the Y chromosome is not affected. However, all daughters of afflicted males become carriers of the trait because they inherit the defective X chromosome. Female carriers have a 50% chance of transmitting the trait to their offspring. Half of the daughters become carriers, and half of their sons have manifestations of hemophilia. Hemophilia A and B are found in all ethnic and racial groups, although a lower prevalence may exist in the Chinese

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