Gender Ethnicracial And Life Span Considerations

Cushing's syndrome in infants usually results from adrenal carcinoma. Primary disease is often linked to a familial autoimmune disorder and is seen in children and young adults of both genders. Secondary disease is more common than primary disease in children older than 6 or 7 and, as in adults, is usually the result of overproduction of ACTH. In adults, secondary Cushing's syndrome that results from pituitary disease is most common in females aged 30 to 50 years. Secondary Cushing's syndrome that results from increased ACTH secretion is more common in males, possibly because of the higher incidence of bronchogenic carcinoma that is caused by smoking. There are no known racial and ethnic considerations.

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