Gender Ethnicracial And Life Span Considerations

Pernicious anemia is the most prevalent form of vitamin B12 deficiency in the United States and is most common in the Great Lakes region and New England. Still, pernicious anemia occurs only in 0.1% of the population. This disorder most commonly affects people older than age 50 years, and the incidence rises as the age increases. Juvenile pernicious anemia, however, has been found in children younger than 10 years of age; generally, it is caused by a congenital stomach disorder that secretes abnormal intrinsic factor. Because their life span is longer, women are more prone to develop pernicious anemia, with African American women more prone to an earlier onset than other populations. Individuals with Northern European descent, in particular those with Celtic (English, Irish, Scottish) or Scandinavian origin, are prone to the condition.

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