Genetic Considerations

While several genetic factors may contribute to susceptibility to cardiogenic shock, no direct genetic link has been documented. Tumor necrosis factor (TNF)-alpha variants have been associated with severe heart failure. Polymorphisms in several genes may be predictors of survival TNF-alpha, interleukin (IL)-6, IL-10, transforming growth factor (TGF)-beta, and interferon (IFN)-gamma cytokine. Persons who carry the TNF-2 allele appear to have better outcomes than persons with other variants of this gene.

0 0

Post a comment