Genetic Considerations

No clear genetic contributions to susceptibility have been defined.

GENDER, ETHNIC/RACIAL, AND LIFE SPAN CONSIDERATIONS

Increased incidence of abruption is noted in those with grand multiparity and advanced maternal age. In addition, the risk of recurrence in a subsequent pregnancy is increased. Abruptions occur in one of 200 deliveries and are responsible for 10% of third-trimester stillbirths. Severe abruptions are associated with a 25% to 35% perinatal mortality rate. Abruptio placentae is more common in African American women than in either white or Latin American women. However, whether this is the result of socioeconomic, genetic, or combined factors remains unclear.

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