population. The prevalence in general follows the racial and ethnic distribution of the U.S. population.

Bleeding abnormalities that are associated with hemophilia are usually noticed when the child becomes active and learns to walk, but mild cases may go undetected until adulthood. Approximately 40% of children have their first bleeding during their first year of life, and by age 4, 90% of children with hemophilia have had episodes of persistent bleeding from minor injuries. Bleeding episodes seem to decrease at or after adolescence, which may be because of the decreased risk of trauma, as well as stabilization of the disease process.

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