Info

Drug Class

Dosage

Description

Rationale

Diuretics

Varies with drug

Thiazides; loop diuretics

Manage fluid overload and congestive symptoms

Calcium channel blockers

Varies with drug

Diltiazem

Depresses impulse formation and conduction

Coronary vasodilators

Varies with drug

Nitroglycerine, nitro-prusside, Captopril, enalapril, hydralazine

Decrease preload and afterload; decrease regurgitant blood flow; reduce ventricular size

Warfarin

Initially 10-15 mg, then 2-10 mg/day maintenance

Anticoagulant

Prevents thrombi from forming on the synthetic valve

Heparin

Initially 80 units/kg IV bolus, followed by an infusion of 18 units/kg; serial APPT monitoring to guide future doses

Anticoagulant

Prevents thrombi initially until warfarin therapy is well regulated

Other Drugs: Inotropic agents (dobutamine [Dobutrex], digoxin) are used to enhance

the hearts pumping ability. If they are present, dysrhythmias are treated with antidys-

rhythmics, such as propranolol (Ind

erai) or quinidine.

0 0

Post a comment