vincristine, imatinib

mal granulocytes

Other Drugs: Interferon therapy, monoclonal antibodies


Management focuses on providing comfort, support, and patient education and managing complications. Determine how the patient is coping with the disease and where you can best provide support. For some patients, improving their comfort is the highest priority, either physically, such as with a bed bath or back rub, or emotionally, such as by listening to fears and concerns and providing interesting distractions. Teach stress- and pain-reduction techniques. Provide mouth care to lessen the discomfort from oral lesions. Support the patient's efforts to maintain grooming and a positive body image.

Institute measures to control infection and maintain a safe environment. To limit the risk of bleeding, hold firm pressure on all puncture wounds for at least 10 minutes or until they stop oozing. Limit the use of intramuscular injections and intravenous catheter placement when the patient is pancytopenic. Avoid taking rectal temperatures, using rectal suppositories, or performing a rectal examination.

Assist the patient in minimizing the discomfort of splenomegaly. Provide small, frequent meals. Maintain adequate fluid intake and a high-bulk diet. Prevent constipation. Encourage the patient to cough and perform deep-breathing exercises as a prophylactic for atelectasis.

For patients who are undergoing outpatient chemotherapy, teach about side effects, emphasizing dangerous ones such as bone marrow suppression. Emphasize that the physician should be called in case of a fever over 100°F, chills, redness or swelling, a sore throat, or a cough. Explain the signs of thrombocytopenia. Emphasize that the patient needs to avoid aspirin or aspirin-containing compounds that might exacerbate bleeding. Emphasize the need for adequate rest and the importance of a high-calorie, high-protein diet.

If the patient does not respond to treatment, be honest about prognosis. Implement strategies to manage pain, fever, and infection to ensure the patient's comfort. Work with the patient, significant others, and chaplain to help the patient plan for a terminal illness and achieve a compassionate death.

Constipation Prescription

Constipation Prescription

Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. Sometimes you just want everyone to leave you alone and sleep to escape the pain. It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life.

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