Info

Drug Class

Dosage

Description

Rationale

Diuretics

Varies by drug

Furosemide, mannitol

Assist in managing intracranial hypertension (although their use remains controversial)

Sedatives

Varies by drug

Short-acting sedatives: midazolam, propofol (Diprivan), fentanyl

Control intermittent increases in ICP with a resultant decrease in CPP; short action of drugs allows for temporarily stopping infusion so that neurological assessment can be performed

Chemical

Varies by drug

Mivacurium,

Improves oxygenation and ventilation

paralysis

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