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5.9 days

MEDICAL: Malignancy, Female Reproductive System with CC 354

5.9 days

SURGICAL: Uterine, Adnexa Procedure for Non-Ovarian/ Adnexal Malignancy with CC

Cancer of the cervix is one type of primary uterine cancer (the other being uterine-endome-trial cancer) and is predominately epidermoid. Invasive cervical cancer is the third most common female pelvic cancer. It is estimated that 3710 women will die from cervical cancer in 2005. The death rate from cervical cancer has steadily declined over the past 50 years owing to the increased use of the Papanicolaou exam, which detects cervical changes before cancer develops.

Cervical cancer is of three types: dysplasia, carcinoma in situ (CIS), and invasive carcinoma. In dysplasia, the lower third of the epithelium contains abnormal cells with the earliest form of premalignant changes. These changes are considered preinvasive, and the atypical cells have some degree of surface maturation. CIS is carcinoma confined to the epithelium. The full thickness of the epithelium contains abnormally proliferating cells. Both dysplasia and CIS are considered preinvasive cancers and, with early detection, have a 5-year survival rate of 73% to 92%.

Invasive carcinoma occurs when cancer cells penetrate the basement membrane. Metastasis occurs through local invasion and by way of the lymphatic ducts. As many as 10 years can elapse between the preinvasive and the invasive stages. A further 5 years can be added if one considers the precancerous changes that occur in atypical cells and dysplasia as the first step of malignancy.

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