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3.7 days

MEDICAL: Benign Prostatic Hypertrophy with CC 336

4.0 days

SURGICAL: Transurethral Prostatectomy with CC

Benign prostatic hyperplasia (BPH; excessive proliferation of normal cells in normal organs) or hypertrophy (an increase in size of an organ), one of the most common disorders of older men, is a nonmalignant enlargement of the prostate gland. It is the most common cause of obstruction of urine flow in men and results in more than 4.5 million visits to healthcare providers annually in the United States. The degree of enlargement determines whether or not bladder outflow obstruction occurs. As the urethra becomes obstructed, the muscle inside the bladder hypertrophies in an attempt to assist the bladder to force out the urine. BPH may also cause the formation of a bladder diverticulum that remains full of urine when the patient empties the bladder.

As the obstruction progresses, the bladder wall becomes thickened and irritable, and as it hypertrophies, it increases its own contractile force, leading to sensitivity even with small volumes of urine. Ultimately, the bladder gradually weakens and loses the ability to empty completely, leading to increased residual urine volume and urinary retention. With marked bladder distension, overflow incontinence may occur with any increase in intra-abdominal pressure such as that which occurs with coughing and sneezing. Complications of BPH include urinary stasis, urinary tract infection, renal calculi, overflow incontinence, hypertrophy of the bladder muscle, acute renal failure, hydronephrosis, and even chronic renal failure.

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