5.3 days

MEDICAL: Malignancy, Male Reproductive System, with CC 338

3.7 days

SURGICAL: Testes Procedures, for Malignancy

The American Cancer Society estimated that approximately 8000 new cases of testicular cancer would be diagnosed in 2005 and 390 men would die from this disease. The cure rate exceeds 90% and the 5-year survival rate is 72%. The risk of developing this cancer is 1 in 300. Testicu-lar cancer is a rare tumor that arises from the germinal cells (cells that produce sperm) of the embryonal tissues and causes less than 1% of all cancer deaths in men. Testicular tumors are classified as seminomas or nonseminomas. Seminomas are composed of uniform, undifferenti-ated cells that resemble primitive gonadal cells. This type of tumor represents 40% of all tes-ticular cancer and is usually confined to the testes and retroperitoneal nodes. There are two types of seminomas: classical (occur between the late 30s and early 50s) and spermatocytic

880 Testicular Cancer seminomas (occur around age 55, grow slowly, and do not metastasize). Nonseminomas show varying degrees of cell differentiation and include embryonal carcinoma (occur most often in 20- to 30-year-olds, grows rapidly, and metastasizes), teratoma (can occur in children and adults), choriocarcinoma (rare and highly malignant), and yolk cell carcinoma derivatives (most common in children up to 3 years of age and have a very good prognosis). Sometimes, testicular tumors are "mixed," containing elements distinctive to both groups.

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