Mean LOS 45 days Description Medical Other Circulatory System Diagnoses with CC

Pericarditis is an inflammation of the pericardium, which is the membranous sac that encloses the heart and great vessels. The inflammatory response causes an accumulation of leukocytes,

714 Pericarditis platelets, fibrin, and fluid between the parietal and the visceral layers of the pericardial sac, thus producing a variety of symptoms, depending on the amount of fluid accumulation, how quickly it accumulates, and whether the inflammation resolves after the acute phase or becomes chronic.

An acute pericardial effusion is caused by an accumulation of fluid in the pericardial sac. The fluid accumulation interferes with cardiac function by compressing the cardiac chambers. Chronic constrictive pericarditis usually begins as an acute inflammatory pericarditis and progresses over time to a chronic, constrictive form because of pericardial thickening and stiffening. The thickened, scarred pericardium becomes nondistensible and decreases diastolic filling of the cardiac chambers and cardiac output. Chronic pericardial effusion is a gradual accumulation of fluid in the pericardial sac. The pericardium is slowly stretched and can accommodate more than 1 L of fluid at a time.

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