Pharmacologic Highlights

Medication or Drug Class



Demeclocycline (Declomycin)

Varies with drug

600 mg-1200 mg/day in two or three divided doses PO

Thiazide diuretics; loop diuretics (furosemide)

Antibiotic: tetracycline derivative

Remove excess fluid volume (may be used in patients with cardiac symptoms)

Blocks action of ADH at distal and collecting tubules of the kidney

Other Tests: Blood urea nitrogen, urine specific gravity, urine sodium, radioimmunoassay of ADH

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