Accessing Blast Programs And Documentation

The National Center for Biotechnology Information (NCBI) currently supports two versions of BLAST free of charge: BLAST 2.0 (gapped BLAST) and Position-Specific Iterated BLAST (PSI-BLAST). BLAST 2.0 is the standard version of BLAST, which allows a user to search a sequence database with a nucleotide or protein sequence of interest. BLAST 2.0 places gaps into the query and target sequences so that separate areas of similarity between the two sequences can be returned as one hit. PSI-BLAST is an iterative BLAST search, which is optimized for finding distantly related sequences.

Other BLAST programs are also available from the NCBI Web page. "BLAST 2 sequences" uses the BLAST search engine to produce an alignment of two sequences entered by the user. On the Specialized BLAST pages, researchers can use the BLAST engine to search sequences that are not in GenBank. At present, these databases include unfinished microbial genomes, P. falciparum (the human malaria parasite), and tentative

Contributed by Tyra G. Wolfsberg and Thomas L. Madden

Current Protocols in Protein Science (1999) 2.5.1-2.5.29 Copyright © 1999 by John Wiley & Sons, Inc.

Computational Analysis

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Understanding SEO Help People Find Your Business

Understanding SEO Help People Find Your Business

So what does SEO stand for and what does it do for your offline business? Search Engine Optimization is the official title and you can see why it is commonly abbreviated. If you are wondering about SEO then you either have a new website or are considering setting one up. SEO comes in to play once your site is live on the web. After all you now have to get visitors to actually see your site. In SEO terms attracting visitors is known as generating traffic and this can be achieved by using search engine optimization tactics.

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