Female

The incidence of cancer in the U.S. roughly doubles every S years after age 25; therefore, cancer most commonly affects older adults.

2. In most organs, the most common malignancy is metastatic. Do not be fooled into saying that hepatocellular cancer is the most common malignancy of the liver if metastatic cancer is a choice. Unless the question specifically asks for a primary tumor, do not assume that a primary tumor is the answer.

3. Metastases to the spine can cause cord compression (local spinal pain, reflex changes, weakness, sensory loss, paralysis). Cord compression is an emergency, and the first step is to start high -dose corticosteroids.Then get an MRl.The next step is to (real with radi ation. Surgical decompression is used if radiation fails or the tumor is known not to be radiosensitive. Prompt intervention is essential, and outcome is closely linked to pretreat-ment function.

Genetic predisposition to cancer

DISEASE/SYNDROME Retinoblastoma MEN, type 1 MHN, type TIa MEN, type lib Familial polyposis coli Gardner syndrome Turcot syndrome Peulz-feghers syndrome

Neurofibromatosis,.. type 1

Neurofibromatosis, type 2

Tuberous sclerosis .

Von HippeCLindau disease

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