Drug Eruptions in Dermatology

Rosacea Free Forever

Rosacea Free Forever Cure

Get Instant Access

Typical presentations (in descending order of frequency):

Exanthema (maculopapular, morbilliform)

Urticaria and angioedema

Fixed drug eruptions

Erythema multiforme

Stevens-Johnson syndrome

Exfoliative dermatitis

Photosensitivity reactions

Anaphylaxis

Toxic epidermal necrolysis

Drugs most commonly resulting in an adverse skin reaction: Amoxicillin

Trimethoprim-sulfamethoxazole

Ampicillin

Whole blood

Cephalosporins

Allopurinol

Carbamazepine

Drugs Causing Skin Pigmentation Changes

Color

Drug

Blue-gray

Gold

Brown

ACTH, bleomycin, minocycline, oral contraceptives, zidovudine

Gray

Amiodarone, antimalarials, minocy-cline, phenothiazines

Red

Clofazimine

Yellow

Beta-carotene, quinacrine

Drug Eruptions & Likely Patterns

Drug

Pattern of Eruption

Antimalarials

Lichen planus-like eruption

Barbiturates

Blistering of lower limbs

Beta-blockers

Psoriasiform

Iodides and bromides

Acneiform eruption

Minocycline

Hyperpigmentation

Penicillamine

Pemphigus-like eruption

Penicillins, sulfonamides

Morbilliform, erythema multiforme, SLE

Phenothiazines

Photosensitive dermatosis

Salicylates

Angioedema, urticaria

Skin Reaction Patterns & Drugs That Cause Them

Reaction Pattern

Likely Drugs

Acne

Corticosteroids, lithium

Alopecia

Anti-thyroid drugs, coumarin anticoagulants, cytotoxics (e.g., chemo)

Erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis

Allopurinol, antibiotics, anticonvulsants, NSAIDs, sulfonamides

Erythema nodosum

Oral contraceptives, sulfonamides

Erythroderma

Antibiotics, anti-rheumatic drugs

Exfoliative dermatitis

Gold, isoniazid, phenylbutazone

Photosensitivity

Phenothiazines, tetracyclines

Psoriasiform eruptions

Antimalarials, beta-blockers, lithium

SLE-like syndrome

Hydralazine, minocycline, penicillin, sulfonamides

(Continued text on following page)

Skin Reaction Patterns & Drugs That Cause Them (Cont'd)

Reaction Pattern Likely Drugs

Toxic erythema Antibiotics (e.g., ampillicin), anti-

rheumatics, barbiturates, sulfonamides Vasculitic and Indomethacin, phenytoin purpuric eruptions

Was this article helpful?

0 0
How To Deal With Rosacea and Eczema

How To Deal With Rosacea and Eczema

Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.

Get My Free Ebook


Post a comment