The future for hair growth research and potential forms of treatment is very bright. The cross-disciplinary efforts of academia, the pharmaceutical industry, and clinicians have led to new understanding of hair growth regulation, both biochemically and genetically. Sawaya and Price (8) have recently shown that there are differences in the amounts of steroid-metabolizing enzymes in the hair follicles of males and females with androgenetic alopecia. The isolation of two forms (type I and type II) of the enzyme 5a-reductase requires further study to elucidate their specific roles in regulation of hair follicle growth/regression. The recent finding that the enzyme aromatase is specifically located in the outer root sheath of hair follicles refocuses our efforts to study the entire hair follicle, not just the dermal papilla cells (8). Based on the numerous patent applications since 1995 |
(1), it is clear that industry is highly involved in developing hair growth enhancers. And finally, Ahmad and colleagues' (44) discovery of the gene for hair < loss in alopecia universalis provides momentous progress at the molecular level. These exciting findings highlight the great strides that have been made in hair
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