Info

Polypodium leu-cotomos (trop-ical fem) ex-tract Polypodium leu-cotomos (trop-ical fem) ex-tract

Epigallocat-echin-3-gallate Apigenin Silymarin

N-acetyl-

cysteine Captopril Other thiols N-acetyl-cysteine

Guinea pigs, human

Human

Mouse

Mouse Mouse

Skin tumor incidence Erythema (skin color)

Erythema (MED), immediate pigment darkening, delayed tanning, minimal phototoxic dose, and histology Skin tumor incidence

Skin tumor incidence Edema, sunburn and apoptotic cell formation, and skin tumor incidence UVA-induced binding of 8-MOP and CPZ to epidemial biomac-romolecules DNA synthesis rate

Protective

Protection against UVR-and PUVA-induced damage

Protection against UVR-and PUVA-induced damage

Protective

Protective Protective

N-acetyl-cysteine and Captopril most protective thiols

Protective

Green tea contains catechin and epi- Wang et al., 1991

catechin derivatives Extract with immunomodulating properties

Not immunosuppressive; isolated from green tea

Isolated from milk thistle plant

Vitamin E less protective

N-acetyl- Rat cysteine Several cysteine derivatives Melatonin Human

UVA-induced binding of Protective 8-MOP and CPZ to epidermal biomac-romolecules Erythema (skin color) Protective

Melatonin

Human

Erythema (skin color) Protective

Melatonin

Human

Superoxide dis- Guinea pig mutase

Erythema (skin color and Protective skin blood flow)

PUVA-induced erythema Protective and edema

Superoxide dis- Guinea pig mutase Superoxide dis- Human mutase

Erythema

Erythema (skin color)

Not protective

Protective when applied occlusively after UVR exposure

Superoxide dis- Mice, human PUVA-induced erythema Protective mutase and edema

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