Acute alcoholic myopathy (rhabdomyolysis) may cause painful, tender swelling of one or more large muscle groups. Diagnosis depends on a high index of clinical suspicion, elevation of serum creatine phosphokinase, and myoglobinuria. Chronic alcoholic myopathy may accompany alcoholic polyneuropathy, presenting as painless, progressive muscle weakness and wasting.
The development of osteoporosis in middle-age men is uncommon except in male alcoholics, where decreased bone mass has been documented (Turner, 2000). In women, improvement in bone mass has been shown with moderate alcohol use, especially in postmenopausal women (Laitinen et al., 1993).
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