Glandular Cells In Ureteral Washing

Pap Smear Urothelial Cell

Size limits of this volume preclude a complete description of the various uncommon lesions of the urinary tract. The interested reader is referred to the classic texts of Koss, and other books relative to urinary cytology. Squamous carcinoma and adenocarcinoma are infrequent cancers in the bladder, but have the same characteristics as those lesions elsewhere in the body Figs. 5.1-5.3 . The microscopist should resist the temptation to call a urothelial lesion squamous or glandular when areas of...

Atypical Urothelial Cells Indeterminate for Neoplasia

Urothelial Cytology

Unfortuntely, as in every other body site, cytologic samples from the urinary tract are not always readily placed into distinct categories. An atypical interpretation is appropriate when morphologic changes exceed those described as benign cellular changes, but lack clear signs of neoplasia Figs. 2.7, 2.15, 2.33 . This is generally encountered when dealing with a sample from a patient with a low grade lesion, especially those called low malignant potential LMP , or in the presence of severe...

Mimics of High Grade Carcinoma Table 7 Polyoma Virus Figs 344352

Benign Urothelial Cells Urine

The most frequently encountered cellular mimic of high grade urothelial carcinoma is produced by infection with polyoma BK virus. Infection can occur in otherwise healthy people, but more commonly is seen in immunocompromised patients, especially renal transplant and HIV infected individuals. When the virus infects patients with high grade bladder cancer, the diagnosis of both or either can be extremely difficult. If the sample is heavily populated with apparently infected cells and cancer...